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Related Concept Videos

Insomnia01:27

Insomnia

623
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
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Management of Insomnia01:19

Management of Insomnia

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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

7.6K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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Cancer02:18

Cancer

51.8K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cancer Therapies02:49

Cancer Therapies

8.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Related Experiment Video

Updated: May 6, 2026

Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
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Cancer-related insomnia.

Raghava R Induru1, Declan Walsh2

  • 1The Harry R. Horvitz Center for Palliative Medicine, Cleveland, OH, USA Department of Solid Tumor Oncology, Section of Palliative Medicine and Supportive Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA.

The American Journal of Hospice & Palliative Care
|October 22, 2013
PubMed
Summary

Insomnia significantly worsens cancer symptom burden and quality of life for patients and families. Effective management strategies, including nonpharmacologic therapies and symptom-specific treatments, are crucial for improving patient outcomes.

Keywords:
cancerinsomniaquality of lifesymptomstherapeutics

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Area of Science:

  • Oncology
  • Sleep Medicine
  • Psycho-oncology

Background:

  • Insomnia is a prevalent issue in cancer patients, exacerbating symptom burden and diminishing quality of life.
  • Management challenges stem from a lack of standardized definitions and treatment protocols for cancer-related insomnia.
  • Certain cancer types (lung, breast, head and neck) and demographics (older women) show higher susceptibility.

Purpose of the Study:

  • To review the impact of insomnia on cancer patients and explore current management strategies.
  • To highlight the need for systematic screening and validated assessment tools for cancer-related insomnia.
  • To discuss therapeutic options, including nonpharmacologic and pharmacologic interventions.

Main Methods:

  • Systematic literature review of studies on insomnia in cancer patients.
  • Analysis of existing definitions, assessment scales, and treatment approaches.
  • Evaluation of nonpharmacologic (e.g., cognitive behavioral therapy) and pharmacologic interventions.

Main Results:

  • Insomnia is common across various cancer types, particularly lung, breast, and head and neck tumors, affecting patients, caregivers, and families.
  • Nonpharmacologic therapies, such as cognitive behavioral therapy, show promise for managing cancer-related insomnia.
  • Newer nonbenzodiazepine hypnotics may offer advantages over older medications, and managing comorbid symptoms is essential.

Conclusions:

  • Effective management of insomnia in cancer patients is critical for improving overall quality of life.
  • Systematic screening and the use of validated assessment tools are recommended.
  • A multimodal approach combining nonpharmacologic therapies, appropriate pharmacologic agents, and management of associated symptoms is key.