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Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
Gastric somatostatinoma: an extremely rare cause of upper gastrointestinal bleeding
Varayu Prachayakul1, Pitulak Aswakul, Morakod Deesomsak
1Division of Gastroenterology, Department of Internal Medicine, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand.
Abstract:
A 49-year-old woman presented with chronic abdominal discomfort, significant weight loss, and chronic intermittent diarrhea. She suddenly developed massive upper gastrointestinal bleeding and was referred for further treatment. Endoscopy indicated a large mass in the upper gastric body with antral and duodenal bulb involvement. Endosonography showed a large well-defined isoechoic gastric subepithelial mass with multiple intra-abdominal and peripancreatic lymphadenopathy, suspected to be malignant on the basis of fine needle aspiration cytology. The tumor was surgically removed, and histopathology showed typical characteristics of a neuroendocrine tumor. On the basis of immunohistochemical staining, somatostatinoma, a rare neuroendocrine tumor, was diagnosed. Gastrointestinal bleeding is a rare presentation and the stomach is an uncommon tumor location.
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