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Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
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Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies
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Using cardiac biomarkers in veterinary practice.

Mark A Oyama1

  • 1Section of Cardiology, Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA.

The Veterinary Clinics of North America. Small Animal Practice
|October 23, 2013
PubMed
Summary
This summary is machine-generated.

Cardiac biomarker testing aids in diagnosing heart disease in pets. Assays like cardiac troponin-I and N-terminal pro-B-type natriuretic peptide help identify disease and assess patient risk.

Keywords:
BNPCardiac biomarkersHeart diseaseNatriuretic peptideTroponin

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Area of Science:

  • Veterinary Medicine
  • Cardiology
  • Biomarker Discovery

Background:

  • Cardiac diseases are a significant concern in canine and feline medicine.
  • Accurate diagnosis and risk assessment are crucial for effective management of heart conditions in pets.

Purpose of the Study:

  • To review the utility of blood-based cardiac biomarker assays in veterinary cardiology.
  • To highlight the role of biomarkers in diagnosing heart disease and predicting outcomes in dogs and cats.

Main Methods:

  • Review of current scientific literature on cardiac biomarkers in companion animals.
  • Focus on cardiac troponin-I and N-terminal pro-B-type natriuretic peptide assays.
  • Analysis of biomarker application in differentiating cardiac vs. non-cardiac respiratory disease and detecting preclinical cardiomyopathy.

Main Results:

  • Cardiac biomarker assays, specifically cardiac troponin-I and N-terminal pro-B-type natriuretic peptide, are valuable diagnostic tools.
  • These tests aid in distinguishing cardiac from non-cardiac causes of respiratory distress.
  • Biomarker testing can detect preclinical cardiomyopathy and assess morbidity and mortality risk in animals with heart disease.

Conclusions:

  • Cardiac biomarker testing is increasingly important in veterinary clinical practice.
  • Effective use requires proper patient selection, accurate result interpretation, and integration with existing diagnostic approaches.
  • Biomarker assays enhance the diagnostic capabilities for heart disease in dogs and cats.