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Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the

Annastasia S Hyde1, Ashley M Thelen, Joseph J Barycki

  • 1From the Department of Biochemistry, University of Nebraska, Lincoln, Nebraska 68588-0664.

The Journal of Biological Chemistry
|October 23, 2013
PubMed
Summary

UDP-glucose dehydrogenase (UGDH) enzyme activity and hyaluronan production depend on its quaternary structure. Maintaining a dimer-hexamer equilibrium is crucial for UGDH

Keywords:
Cardiac DefectsDehydrogenaseEnzyme CatalysisGlycobiologyHuman UGDHHyaluronanHyaluronateProstate CancerProtein ConformationProtein Dynamics

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