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Chronic kidney disease: Obesity in children with end-stage renal disease

Rafael T Krmar1, Peter Bárány

  • 1Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institute, B 57 Huddinge, Karolinska University Hospital, SE-141 86 Stockholm, Sweden.

Nature Reviews. Nephrology
|October 23, 2013
PubMed

Insights

Children with end-stage renal disease, especially those who received a kidney transplant, often experience overweight or obesity. Infants with this condition are more likely to be underweight, indicating a need for tailored interventions.

Area of Science:

  • Pediatric Nephrology
  • Childhood Obesity
  • Renal Disease Management

Background:

  • End-stage renal disease (ESRD) significantly impacts pediatric health.
  • Nutritional status in children with ESRD requires careful monitoring.
  • Overweight, obesity, and underweight are critical concerns in this vulnerable population.

Purpose of the Study:

  • To determine the prevalence of overweight and obesity in children with ESRD.
  • To identify specific nutritional challenges in different age groups within the pediatric ESRD population.
  • To underscore the necessity for targeted nutritional interventions in pediatric ESRD.

Main Methods:

  • Retrospective analysis of anthropometric data in pediatric patients with ESRD.
  • Stratification of nutritional status by age group and renal replacement therapy status.
  • Comparison of prevalence rates with established pediatric growth standards.

Main Results:

  • A high prevalence of overweight or obesity was observed in children with ESRD.
  • Renal transplant recipients showed a particularly high incidence of overweight/obesity.
  • Underweight was more common in infants compared to older children with ESRD.

Conclusions:

  • Children with ESRD exhibit significant nutritional abnormalities, including high rates of overweight and obesity.
  • Infants with ESRD face a distinct risk of underweight.
  • Urgent evaluation and implementation of nutritional interventions are crucial for improving outcomes in pediatric ESRD patients.

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