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Updated: May 6, 2026

Investigating the Immunological Mechanisms Underlying Organ Transplant Rejection
Published on: August 20, 2007
Molecular analysis of transplant rejection: marching onward
Fadi G Lakkis1, Timothy R Billiar
1the Department of Surgery University of Pittsburgh School of Medicine, Pittsburgh, PA 15261. F.G. Lakkis is at the Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.
Abstract:
Transcriptional profiling of organ transplants is increasingly defining the biological pathways responsible for graft rejection at the molecular level and identifying gene transcripts that diagnose or predict rejection. These advances hold significant promise for the treatment of organ rejection and for improving clinical outcomes after transplantation, but hurdles remain.
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