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Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
Published on: March 10, 2015
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[Microscopic colitis--new insights relevant to clinical practice].
Zeitschrift Fur Gastroenterologie
|October 23, 2013
Summary
Microscopic colitis, a chronic inflammatory bowel disease causing watery diarrhea, has new developments. Budesonide remains the primary treatment, but long-term strategies require further research for better patient outcomes.
Area of Science:
- Gastroenterology
- Histopathology
- Internal Medicine
Context:
- Microscopic colitis is a chronic inflammatory bowel disease characterized by watery, non-bloody diarrhea.
- It encompasses collagenous colitis, lymphocytic colitis, and a newly identified incomplete subtype.
- Patients often experience abdominal pain, nocturnal diarrhea, urgency, and incontinence.
Purpose:
- To review recent advancements in microscopic colitis relevant to clinical practice.
- To highlight current therapeutic options and unresolved challenges in long-term management.
- To provide an updated overview of this increasingly recognized condition.
Summary:
- Microscopic colitis presents with chronic watery diarrhea and other gastrointestinal symptoms.
- Histological subtypes include collagenous, lymphocytic, and incomplete forms.
- Budesonide is the current evidence-based treatment, though long-term management issues persist.
Impact:
- This review offers insights into new developments for clinicians managing microscopic colitis.
- It addresses the need for improved long-term treatment strategies.
- Enhanced understanding may lead to better patient care and outcomes for this condition.
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