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Updated: May 6, 2026
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
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A very rare bilateral adrenal tumor
Antonio Toniato1, Isabella Merante Boschin, Maria Rosa Pelizzo
12° Surgical Clinic, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, 35128, Padua, Italy, giorgiolina@libero.it.
Endocrine
|October 23, 2013
Summary
This study details a rare case of bilateral adrenal incidentalomas that were histologically diagnosed as solitary fibrous tumors (SFTs). Surgical excision is the primary treatment for adrenal SFTs, with recurrence linked to incomplete removal.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Solitary fibrous tumors (SFTs) are uncommon mesenchymal neoplasms.
- Adrenal gland localization of SFT is exceptionally rare, with only five reported cases.
Observation:
- A 54-year-old patient presented with bilateral adrenal incidentalomas.
- Histological examination revealed these incidentalomas to be solitary fibrous tumors.
Findings:
- Immunohistochemical analysis showed SFTs can be positive for CD34, vimentin, CD99, and bcl-2.
- SFTs are typically negative for cytokeratins, chromogranin A, NSE, neurofilaments, synaptophysin, and S-100.
Implications:
- Surgical excision is the standard treatment for adrenal SFTs.
- Locoregional recurrence is associated with positive surgical margins, indicating incomplete excision.
- Distant metastases are linked to atypical or malignant features of the tumor.
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