Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Modular, Enantioselective Entry into Polysubstituted Shapeshifting Molecules.

Journal of the American Chemical Society·2024

Same author

A Shapeshifting Roadmap for Polycyclic Skeletal Evolution.

Journal of the American Chemical Society·2023

Same author

Melanoma Antigen Recognized by T Cells With Blue Chromogen Improves Identification of Melanocytes From Background Melanized Keratinocytes on Frozen Sections.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2023

Same author

Taming Shapeshifting Anions: Total Synthesis of Ocellatusone C.

Journal of the American Chemical Society·2022

Same author

Study of the telomerase hTERT fraction, PCNA and CD34 expression on pituitary adenomas. Association with clinical and demographic characteristics.

Journal of neuro-oncology·2007

Same author

Human telomerase and alpha-methylacyl-coenzyme A racemase in prostatic carcinoma. A comparative immunohistochemical study.

Annals of diagnostic pathology·2006

Same journal

Patient Safety Monitoring in International Laboratories.

MLO: medical laboratory observer·2026

Same journal

Taking issue with some OIG recommendations.

MLO: medical laboratory observer·2018

Same journal

PCR then and now Improvements to technologies expand clinical utilization.

MLO: medical laboratory observer·2018

Same journal

Outsourcing vs. insourcing Which strategy is the better way for labs to support their larger institution?

MLO: medical laboratory observer·2018

Same journal

The autoimmune response and neuropsychiatric disorders.

MLO: medical laboratory observer·2018

Same journal

Pathogen discovery through deep sequencing.

MLO: medical laboratory observer·2018

See all related articles

Search research articles

Related Experiment Video

Updated: May 6, 2026

Histological-Based Stainings Using Free-Floating Tissue Sections

Histological-Based Stainings Using Free-Floating Tissue Sections

Published on: August 25, 2020

Surface modified slides let IHC laboratories do more with less

Alfonso Heras¹, Andre Sanchez

¹Bio SB, Inc.

MLO: Medical Laboratory Observer

|October 24, 2013

Summary

No abstract available in PubMed .

More Related Videos

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System

Published on: May 3, 2018

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014

Related Experiment Videos

Last Updated: May 6, 2026

Histological-Based Stainings Using Free-Floating Tissue Sections

Histological-Based Stainings Using Free-Floating Tissue Sections

Published on: August 25, 2020

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System

Automated Slide Scanning and Segmentation in Fluorescently-labeled Tissues Using a Widefield High-content Analysis System

Published on: May 3, 2018

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Anti-Nuclear Antibody Screening Using HEp-2 Cells

Published on: June 23, 2014