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Narrow-band ultraviolet B phototherapy in childhood
Bilge Bulbul Sen1, Emine Nur Rifaioglu, Ozlem Ekiz
1Department of Dermatology, School of Medicine, Mustafa Kemal University , Hatay , Turkey and.
Insights
Narrow-band ultraviolet B (UVB) phototherapy effectively treats childhood skin conditions like vitiligo and psoriasis. This study found it to be a safe and well-tolerated treatment option for pediatric patients.
Area of Science:
- Pediatric Dermatology
- Phototherapy Research
- Dermatological Treatments
Background:
- Narrow-band ultraviolet B (UVB) phototherapy is utilized for pediatric skin conditions.
- Concerns regarding potential skin cancer risk have limited its use in children.
- This study aimed to assess the efficacy and safety of narrow-band UVB phototherapy in pediatric patients with various skin diseases.
Observation:
- The study retrospectively analyzed data from 77 children (aged 5-16) undergoing narrow-band UVB phototherapy.
- Vitiligo (47%) and psoriasis (39%) were the most common conditions treated.
- A total of 81 treatment courses were administered over 4.5 years.
Findings:
- 44.2% of patients achieved a complete response, with others showing good to partial improvement.
- Only 14.3% of patients experienced acute side effects.
- The treatment demonstrated significant efficacy across different pediatric skin conditions.
Implications:
- Narrow-band UVB phototherapy is confirmed as an effective treatment for childhood skin diseases.
- The therapy is well-tolerated, with a low incidence of acute side effects in pediatric patients.
- Findings support the broader application of narrow-band UVB phototherapy in pediatric dermatology.
Background:
Narrow-band ultraviolet B (UVB) has been used for skin diseases in children. However, the use of phototherapy in childhood has limited due to the possible risk of skin cancer. The aim of this study is to evaluate the efficacy and safety of the narrow-band UVB phototherapy in children for the treatment of various skin diseases.
Methods:
The data of the children aged 16 years or under who were treated with narrow-band UVB in our clinic's phototherapy unit were analyzed, retrospectively.
Results:
The study included 77 children (42 girls, 35 boys) aged 5-16 years (mean 12.18 ± 3.53) who were treated with a total of 81 courses of narrow-band UVB phototherapy in the last 4.5 years. The majority of patients had vitiligo (47%) and psoriasis (39%). Thirty-four (44.2%) patients showed complete response, 15 (19.5%) good response, 12 (15.6%) partial response, 5 (6.5%) poor response and 11(14.3%) no response. Acute side effects of phototherapy were observed only in 11 (14.3%) patients.
Conclusions:
Narrow-band UVB phototherapy is an effective and well-tolerated treatment in childhood.
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