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Hemimegalencephaly can present with unusual mid-sagittal structures. This study investigates if these band-like formations seen on MRI are aberrant fibers in unilateral hemimegalencephaly.

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Area of Science:

  • Neuroimaging
  • Neuroradiology
  • Neuroscience

Background:

  • Hemimegalencephaly is a rare congenital brain malformation.
  • Mid-sagittal band-like structures between lateral ventricles are often observed in hemimegalencephaly on MR imaging.

Purpose of the Study:

  • To describe the clinical presentation and MR imaging findings in a patient with unilateral hemimegalencephaly.
  • To investigate the nature of mid-sagittal band-like structures using advanced MR techniques, specifically diffusion tensor MR and fiber tract reconstruction.
  • To determine if these structures represent aberrant mid-sagittal fibers.

Main Methods:

  • Retrospective examination of MR images from a 14-year-old boy with unilateral hemimegalencephaly.
  • Utilized conventional MR imaging, diffusion tensor MR, and fiber tract (FT) reconstruction.
  • Analyzed morphologic abnormalities and clinical presentation.

Main Results:

  • Detailed description of the clinical presentation and morphologic abnormalities.
  • Conventional MR imaging revealed characteristic findings of unilateral hemimegalencephaly.
  • Diffusion tensor MR and fiber tract reconstruction were employed to analyze the mid-sagittal structures.

Conclusions:

  • The study aimed to elucidate the origin of enigmatic mid-sagittal structures in hemimegalencephaly.
  • Advanced MR techniques were used to differentiate these structures from normal white matter tracts.
  • Findings contribute to understanding the complex neuroanatomy in hemimegalencephaly.