Related Experiment Video
Updated: May 6, 2026
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
Aberrant Mid-Sagittal Fiber Tracts Visualized by Diffusion Tensor MR. A Case Report
F Ormitti1, A Summa, E Ventura
1Neuroradiology Unit, Parma University Hospital; Parma, Italy - formitti@ao.pr.it.
Abstract:
In hemimegalencephaly, MR imaging often reveals mid-sagittal band-like structures between the lateral ventricles. We describe the clinical presentation, morphologic abnormalities, conventional MR imaging, diffusion tensor MR and fiber tract (FT) reconstruction in a 14-year-old boy with unilateral hemimegalencephaly. We retrospectively examined MR images to determine whether these structures are aberrant mid-sagittal fibers.
Insights
Hemimegalencephaly can present with unusual mid-sagittal structures. This study investigates if these band-like formations seen on MRI are aberrant fibers in unilateral hemimegalencephaly.
Area of Science:
- Neuroimaging
- Neuroradiology
- Neuroscience
Background:
- Hemimegalencephaly is a rare congenital brain malformation.
- Mid-sagittal band-like structures between lateral ventricles are often observed in hemimegalencephaly on MR imaging.
Purpose of the Study:
- To describe the clinical presentation and MR imaging findings in a patient with unilateral hemimegalencephaly.
- To investigate the nature of mid-sagittal band-like structures using advanced MR techniques, specifically diffusion tensor MR and fiber tract reconstruction.
- To determine if these structures represent aberrant mid-sagittal fibers.
Main Methods:
- Retrospective examination of MR images from a 14-year-old boy with unilateral hemimegalencephaly.
- Utilized conventional MR imaging, diffusion tensor MR, and fiber tract (FT) reconstruction.
- Analyzed morphologic abnormalities and clinical presentation.
Main Results:
- Detailed description of the clinical presentation and morphologic abnormalities.
- Conventional MR imaging revealed characteristic findings of unilateral hemimegalencephaly.
- Diffusion tensor MR and fiber tract reconstruction were employed to analyze the mid-sagittal structures.
Conclusions:
- The study aimed to elucidate the origin of enigmatic mid-sagittal structures in hemimegalencephaly.
- Advanced MR techniques were used to differentiate these structures from normal white matter tracts.
- Findings contribute to understanding the complex neuroanatomy in hemimegalencephaly.
