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Hippocampal asymmetry with hippocampal sulcus remnants in a patient with mild cognitive impairment. A case report

R Conforti1, F M Ronza, A Di Costanzo

  • 1Second University of Naples; Naples, Italy - renata.conforti@unina2.it.

The Neuroradiology Journal
|October 24, 2013
PubMed

Insights

This study details MRI findings in a 65-year-old woman with mild cognitive impairment (MCI). Key observations include hippocampal sulcus remnants and left hippocampal atrophy, suggesting potential links to cognitive decline.

Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Mild cognitive impairment (MCI) is a clinical syndrome that may precede dementia.
  • Magnetic Resonance Imaging (MRI) is crucial for evaluating brain structures in cognitive disorders.

Purpose of the Study:

  • To analyze MRI findings in a patient with MCI.
  • To correlate neuroimaging results with clinical presentation.
  • To review literature regarding hippocampal changes in cognitive impairment.

Main Methods:

  • A 65-year-old female patient diagnosed with MCI underwent brain MRI.
  • Quantitative measurements of hippocampal sulcus remnants and fimbriosubicular distance were performed.
  • Findings were compared with existing literature.

Main Results:

  • MRI revealed bilateral hippocampal sulcus remnants, more prominent on the right.
  • Significant left hippocampal atrophy was observed.
  • Increased left fimbriosubicular distance (2.0 mm) compared to the right (1.2 mm) was noted.

Conclusions:

  • The observed hippocampal atrophy and increased fimbriosubicular distance may be indicative of neurodegeneration in MCI.
  • These imaging biomarkers warrant further investigation in the context of cognitive decline.
  • Correlation of imaging findings with clinical progression is essential for understanding MCI.

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