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Updated: Aug 14, 2026

High-throughput Detection Method for Influenza Virus
Published on: February 4, 2012
Interferon induction by viruses. XIII. Detection and assay of interferon induction-suppressing particles
Abstract:
An assay is described for detecting and measuring the capacity of a single virus particle to suppress completely the yield of interferon from a cell otherwise competent to product interferon. The assay defines virus populations in terms of a newly quantifiable attribute--interferon induction-suppressing particles (ISP). The antagonistic actions of interferon-inducing particles and interferon induction-suppressing particles are thought to determine the interferon-inducing capacity intrinsic to a virus population.
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