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Magnetic Resonance Imaging

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Updated: May 6, 2026

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

High resolution myocardial first-pass perfusion imaging with extended anatomic coverage.

Daniel Stäb¹, Tobias Wech, Felix A Breuer

¹Institute of Radiology, University of Würzburg, Würzburg, Germany.

Journal of Magnetic Resonance Imaging : JMRI

|October 24, 2013

Summary

Parallel Imaging (PI) and Compressed Sensing (CS) were compared for myocardial perfusion imaging. PI demonstrated superior accuracy without systematic errors, making it preferable for clinical studies.

Keywords:

CAIPIRINHA cardiac imaging compressed sensing multislice myocardial perfusion parallel imaging

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Last Updated: May 6, 2026

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Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging

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Published on: February 10, 2012

Area of Science:

Cardiovascular Imaging
Magnetic Resonance Imaging
Medical Physics

Background:

High-resolution myocardial perfusion imaging is crucial for diagnosing cardiac conditions.
Simultaneous multislice (SMS) excitation enables extended anatomic coverage in cardiac MRI.
Advanced reconstruction techniques are needed to balance resolution, coverage, and image quality.

Purpose of the Study:

To compare Parallel Imaging (PI) and Compressed Sensing (CS) frameworks for SMS-based myocardial perfusion imaging.
To evaluate their performance in high-resolution, contrast-enhanced first-pass imaging.
To assess reconstruction accuracy and identify potential errors.

Main Methods:

Simultaneous multislice imaging with MS-CAIPIRINHA was employed for extended coverage.
Equidistant or random undersampling schemes were used with PI and CS reconstruction.
Simulations and in vivo measurements were conducted to compare reconstruction accuracy using comprehensive quality metrics.

Main Results:

Both PI and CS frameworks achieved good reconstruction accuracy for myocardial perfusion imaging.
PI showed low to moderate noise enhancement.
CS exhibited systematic errors and introduced spatiotemporal blurring.

Conclusions:

Both PI and CS enable high-resolution (2.0 × 2.0 mm²) perfusion measurements across six slices per heartbeat.
Parallel Imaging is considered superior for clinical applications due to its lack of systematic deviations.
PI offers a more robust and reliable approach for myocardial perfusion assessment.