Related Experiment Video
Updated: May 6, 2026
06:02
Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
11.2K
Group specific vein-atlasing: an application for analyzing the venous system under normal and multiple sclerosis
Günther Grabner1, Assunta Dal-Bianco, Simon Hametner
1Medical University of Vienna, MR Centre of Excellence, Department of Biomedical Imaging and Image-Guided Therapy, Vienna, Austria.
Journal of Magnetic Resonance Imaging : JMRI
|October 24, 2013
Summary
A novel vein atlas created from healthy individuals reveals significantly higher venous volume in multiple sclerosis (MS) lesions compared to normal-appearing white matter. This atlas aids in evaluating individual venous systems.
Area of Science:
- Neuroimaging
- Vascular Biology
- Multiple Sclerosis Research
Background:
- Understanding the venous system in multiple sclerosis (MS) is crucial for disease characterization.
- Existing methods lack a standardized reference for normal venous anatomy.
Purpose of the Study:
- To develop a group-specific vein atlas from healthy controls.
- To quantify and compare venous volume in MS lesions versus normal-appearing white matter (NAWM) using this atlas.
Main Methods:
- High-resolution 7 Tesla susceptibility-weighted imaging (SWI) and T1-weighted imaging were used.
- Automatic vein segmentation and nonlinear registration created the average vein atlas.
- Venous volume fraction was calculated in MS lesions and NAWM regions.
Main Results:
- The vein atlas successfully visualized the average venous network of healthy controls.
- MS lesions exhibited a significantly higher venous volume fraction compared to the atlas.
- No significant difference in venous volume was observed between NAWM regions and the atlas.
Conclusions:
- The developed vein atlas serves as a valuable tool for assessing population-specific venous systems.
- This atlas enables the evaluation of venous system alterations in individual subjects, particularly in neurological conditions like MS.
Related Concept Videos
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
470
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
470
01:11Overview of Systemic Veins
1.8K
Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
1.8K
01:26Varicose Veins II: Diagnostic Studies and Interprofessional Care
326
Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
326
01:19Imaging Studies VII: Vascular Imaging
568
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
568
01:19Veins of Head and Neck
7.7K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
7.7K
01:26Varicose Veins I: Introduction
384
Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...
384