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TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid
S Wacharasindhu1, S Shuangshoti, S Sunthornyothin
1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Abstract:
Patients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus-the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl-with long-standing untreated lingual hypothyroid-presents with a pathologically proven TSH pituitary macroadenoma and bilateral large ovarian cysts. Although MR imaging may differentiate between hyperplasia and macroadenoma of the pituitary gland, pathological examination is still a cornerstone to correct diagnosis.
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