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HLA-B*13:01 and the dapsone hypersensitivity syndrome

F-R Zhang1, H Liu, A Irwanto

  • 1The authors' full names, degrees, and affiliations are listed in the Appendix.

The New England Journal of Medicine
|October 25, 2013
PubMed
Summary

A genetic marker, HLA-B*13:01, significantly increases the risk of dapsone hypersensitivity syndrome in leprosy patients. This finding could lead to predictive testing, reducing severe drug reactions and mortality.

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