Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Carcinogen-related tumor markers.

D Schmähl, H R Scherf

    Cancer Detection and Prevention
    |January 1, 1985
    PubMed
    Summary

    This study investigated tumor markers from animal experiments using physical and chemical carcinogens. Researchers concluded that no specific tumor markers are reliably induced by these carcinogenic agents.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Formation and persistence of specific purine DNA adducts by 32P-postlabelling in target and non-target organs of rats treated with aristolochic acid I.

    IARC scientific publications·1993
    Same author

    Hexadecylphosphocholine differs from conventional cytostatic agents.

    Journal of cancer research and clinical oncology·1993
    Same author

    Influence of reducing luxury calories in the treatment of experimental mammary carcinoma.

    British journal of cancer·1992
    Same author

    Antitumor activity of alkylphosphocholines and analogues in methylnitrosourea-induced rat mammary carcinomas.

    Progress in experimental tumor research·1992
    Same author

    On the long-term toxic risk of dinaline.

    Cancer letters·1991
    Same author

    Activating mutations at codon 61 of the c-Ha-ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice.

    Cancer letters·1991

    Area of Science:

    • Oncology
    • Toxicology
    • Biomarkers

    Background:

    • Tumor markers are crucial for cancer diagnosis and prognosis.
    • Identifying specific markers for carcinogen-induced tumors is essential for understanding carcinogenesis.
    • Previous research has explored various molecular and cellular changes associated with carcinogen exposure.

    Purpose of the Study:

    • To evaluate the existence of specific tumor markers induced by physical and chemical carcinogens in animal models.
    • To determine if distinct carcinogenic agents elicit unique molecular or cellular signatures in induced tumors.

    Main Methods:

    • Animal models were exposed to various physical and chemical carcinogens.
    • Tumors induced by these agents were analyzed for potential markers.
    • Comparative analysis of tumor characteristics across different carcinogen exposures was performed.

    Main Results:

    • Experiments did not identify any specific tumor markers uniquely associated with particular carcinogenic agents.
    • The study found a lack of distinct molecular or cellular signatures that could be attributed to specific carcinogens.
    • Results indicate a generalized response rather than agent-specific markers.

    Conclusions:

    • There are no specific tumor markers induced by distinct physical or chemical carcinogenic agents.
    • The findings suggest that the tumor-inducing mechanisms of different carcinogens may not result in unique, identifiable markers.
    • Further research may be needed to explore other potential indicators of carcinogen exposure or tumor development.

    Related Experiment Videos