Related Experiment Video
Updated: May 6, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
Published on: June 3, 2016
Resistin - from gene expression to development of diabetes
M Sassek1, E Pruszynska-Oszmalek, J Nowacka-Woszuk
1Poznan University of Life Sciences, Department of Animal Physiology and Biochemistry, Poznan, Poland.
Abstract:
Adipocyte-originated hormonal factors, playing a role of signaling particles, are widely engaged in energy control, feeding behavior and general glucose or lipid metabolism. One of them resistin has been suspected to initiate or develop insulin resistance and diabetes. From the moment of discovery of resistin, during last 13 years, numerous investigations put some light on a potential role of this hormone in mammals. In this review knowledge on resistin, including its structure, physiological role related to obesity and diabetes, as well as, gene sequence and phenotypic effects of the identified polymorphisms in human and domestic mammals is discussed.
Related Concept Videos
Type II Diabetes I: Introduction
Cell Specific Gene Expression
Insulin: The Receptor and Signaling Pathways
Type II Diabetes II: Pathophysiology
Type I Diabetes II: Pathophysiology
Type I Diabetes I: Introduction

