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[Vasculitis. New nomenclature of the Chapel Hill consensus conference 2012]

K Holl-Ulrich1

  • 1Konsultations- und Referenzzentrum für Vaskulitisdiagnostik, Institut für Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland, konstanze.holl-ulrich@uksh.de.

Der Pathologe
|October 25, 2013
PubMed

Insights

The 2012 Chapel Hill Consensus Conference (CHCC) nomenclature updates vasculitis classification based on etiopathology and vessel characteristics. It distinguishes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides and replaces eponyms with systematic names for better clarity.

Area of Science:

  • Rheumatology and Pathology
  • Immunology
  • Histopathology

Background:

  • Advances in understanding vasculitis etiopathology and disease courses.
  • The need for updated classification reflecting current scientific knowledge.
  • Limitations of previous nomenclature systems.

Framework:

  • The revised Chapel Hill Consensus Conference (CHCC) 2012 nomenclature.
  • Classification based on etiopathology, vessel size, and inflammation type.
  • Distinction between ANCA-associated vasculitides and immune complex small vessel vasculitis.

Implementation:

  • Replacement of eponyms with systematic names (e.g., granulomatosis with polyangiitis).
  • Inclusion of clinically significant but less recognized vasculitis types.
  • Focus on histopathological relevance and updated diagnostic criteria.

Implications:

  • Improved diagnostic accuracy and classification of vasculitis.
  • Enhanced understanding of disease mechanisms and clinical presentations.
  • Guidance for histopathologists in identifying and classifying vasculitis subtypes.

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