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CO2 laser oral soft tissue welding: an in vitro study
Sajee Sattayut1, Pitinuch Nakkyo, Puntiwa Phusrinuan
1Lasers in Dentistry Research Group, Khon Kaen University, Thailand.
Laser Therapy
|October 25, 2013
Summary
CO2 laser welding did not increase immediate wound strength compared to sutures alone in oral mucosa. However, laser welding showed a higher proportion of wounds remaining closed under stress.
Area of Science:
- Biomedical Engineering
- Oral Surgery
- Wound Healing Research
Background:
- Limited studies explore laser welding for oral mucosa wound closure.
- Investigating novel methods to enhance surgical wound healing is crucial.
Purpose of the Study:
- To compare the immediate tensile strength of oral mucosal wound closure between traditional suturing and CO2 laser welding.
- To evaluate the efficacy of CO2 laser welding as an adjunct to suturing in a pig tongue model.
Main Methods:
- Utilized 40 pig tongue tissue samples with standardized incisions.
- Compared wound closure using sutures alone (control) versus CO2 laser welding followed by sutures (experimental).
- Measured immediate tensile strength using a tensiometer under stereomicroscope.
Main Results:
- The median tensile strength was 30.40 g/cm² for sutures alone and 40.50 g/cm² for laser welding (P=0.58, not significant).
- A higher proportion of laser-welded wounds (35%) remained intact at 120 g/cm² compared to sutured wounds (15%).
Conclusions:
- CO2 laser welding did not significantly improve immediate tensile strength over sutures alone for oral mucosal wounds.
- CO2 laser welding demonstrated a potential benefit by increasing the proportion of wounds resisting dehiscence under stress.

