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Updated: May 6, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Hepatic brucelloma
Letizia Barutta1, Domenico Ferrigno, Remo Melchio
1Emergency Department, Santa Croce and Carle General Hospital, Cuneo, Italy; School of Emergency Medicine, University of Turin, Turin, Italy.
A rare hepatic brucelloma, a liver abscess caused by Brucella melitensis, was diagnosed 33 years after initial infection. Prolonged antibiotic therapy successfully treated the condition without surgery.
Area of Science:
- Infectious Diseases
- Hepatology
- Microbiology
Background:
- Brucellosis is a globally prevalent zoonotic disease with diverse clinical presentations.
- Hepatic brucelloma, a rare complication, involves abscess formation in the liver due to Brucella melitensis infection.
Observation:
- A 59-year-old male presented with hepatic brucelloma 33 years after a resolved acute brucellosis episode.
- Radiological assessment showed a decrease in lesion size following treatment.
Findings:
- Diagnosis was confirmed through laboratory, radiological, and histological findings.
- Prolonged combined antibiotic therapy led to symptom recovery and lesion reduction.
- Surgical intervention was not required for treatment.
Implications:
- This case highlights the potential for late-onset hepatic brucelloma years after initial brucellosis.
- It underscores the efficacy of prolonged antibiotic regimens in managing hepatic brucelloma.
- The findings contribute to understanding the long-term complications and management of brucellosis.
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