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Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
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A stereoselective approach to peptidomimetic BACE1 inhibitors

Stefania Butini1, Emanuele Gabellieri, Margherita Brindisi

  • 1European Research Centre for Drug Discovery and Development (NatSynDrugs), University of Siena, via Aldo Moro 2, 53100 Siena, Italy; Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.

European Journal of Medicinal Chemistry
|October 26, 2013
PubMed

Keywords:
1,4-benzodiazepineADAPPAlzheimer's diseaseBACE1BDZBenzodiazepinesHEAInhibitorsPeptidomimeticsamyloid precursor proteinhydroxyethylamineβ-Secretase

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