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Detection of rotavirus in children with acute gastroenteritis in Porto Velho, Rondonia, Brazil

C A Sandra1, G K Estevam, M Penati

  • 1Laboratório de Microbiologia, Fundação Oswaldo Cruz, Rondônia-Fiocruz, Porto Velho, RO, CEP 78910-210, Brazil.

Archives of Virology
|October 26, 2013
PubMed

Insights

Rotavirus group A (RVA) infection was low in children with acute gastroenteritis. Vaccination appeared to reduce RVA incidence, though the study observed a general decrease in rotavirus diarrhea over time.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Vaccinology

Background:

  • Rotavirus group A (RVA) is a significant cause of acute gastroenteritis in young children.
  • Understanding RVA incidence in relation to vaccination status is crucial for public health strategies.

Purpose of the Study:

  • To determine the prevalence of RVA infection in children with acute gastroenteritis.
  • To assess the impact of rotavirus vaccination on RVA infection rates.

Main Methods:

  • Fecal samples were collected from 591 children aged 0-6 years with acute gastroenteritis.
  • Vaccination status for rotavirus was recorded for all participants.
  • RVA infection was detected using diagnostic testing on fecal samples.

Main Results:

  • The overall proportion of acute diarrhea cases caused by RVA was low.
  • RVA infection was detected in 13.9% of vaccinated children and 21.1% of unvaccinated children.
  • A decrease in rotavirus diarrhea incidence was observed over the study period in both vaccinated and unvaccinated groups.

Conclusions:

  • Rotavirus group A infection represents a small proportion of acute diarrhea cases in the study population.
  • Rotavirus vaccination may be associated with a reduced incidence of RVA diarrhea.
  • Further research is warranted to understand the declining incidence trends.

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