Bioamplification as a bioaccumulation mechanism for persistent organic pollutants (POPs) in wildlife

Persistent organic pollutant bioaccumulation models have generally been formulated to predict bioconcentration and biomagnification. A third bioaccumulation process that can mediate chemical fugacity in an organism is bioamplification.Bioamplification occurs when an organism loses body weight and the chemical partitioning capacity occurs at a rate that is faster than the chemical can be eliminated.Although bioamplification has not been widely recognized as a bioaccumulation process, the potential consequences of this process are significant. Bioamplification causes an increase in chemical fugacity in the animal's tissues and results in there distribution of contaminants from inert storage sites to more toxicologically sensitive tissues. By reviewing laboratory and field studies, we have shown in this paper that bioamplification occurs across taxonomic groups that include, invertebrates,amphibians, fishes, birds, and mammals. Two case studies are presented, and constitute multi-life stage non-steady state bioaccumulation models calibrated for yellow perch and herring gulls. These case studies were used to demonstrate that bioamplification is predicted to occur under realistic scenarios of animal growth and seasonal weight loss. Bioamplification greatly enhances POP concentrations and chemical fugacities during critical physiological and behavioral events in an animal's life history, e.g., embryo development, juvenile stages, metamorphosis, reproduction, migration, overwintering, hibernation, and disease. Consequently,understanding the dynamics of bioamplification, and how different life history scenario scan alter tissue residues, may be helpful and important in assessing wildlife hazards and risks.