Gnawing at Metchnikoff's paradigm

Ronald P Taylor1

  • 1UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE.

Blood
|October 26, 2013
PubMed

In this issue of Blood, Rossi et al provide convincing evidence that extends and generalizes the importance of trogocytosis, a process in which effector cells use Fcg receptors to remove Immunoglobulin G (IgG)-chelated antigens from donor cells. Their work suggests that the process may be beneficial in the context of epratuzumab treatment of autoimmune diseases.

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