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Updated: May 6, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Squamous cell papilloma of the urinary bladder endoscopically mimicking cancer
Dimosthenis Miliaras1, Ioannis Vakalopoulos, Eleftherios Anagnostou
1Laboratory of Histology, School of Medicine, Aristotle University, 54006 Thessaloniki, Greece ; Department of Urology, School of Medicine, Aristotle University, 54635 Thessaloniki, Greece.
Abstract:
Squamous cell lesions of the urinary bladder are generally rare. Herein we describe a case of 74-year-old male patient with a benign squamous cell papilloma. Histologically, the tumor presented extensive keratinization at its surface and showed no nuclear atypia or stromal invasion. The tumor cells were negative for HPV DNA. These lesions are extremely rare, and even though they are considered benign and non-HPV related, they should be followed, since recurrence has been reported.
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