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Updated: May 6, 2026

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
Published on: March 1, 2024
[Oral manifestations of systemic sclerosis]
J M R Michels-van Amelsfort1, H S Brand, J M van Laar
1Uit de afdeling Reumatologie en Klinische Immunologie van bet Universitair Medisch Centrum Utrecht. j.m.van-laar@ncl.ac.uk
Abstract:
Systemic sclerosis is a relatively rare connective tissue disorder, in which a severe and progressive fibrosis of the skin and sometimes also of internal organs often develops as a result of an increased deposition of collagen. Fibrosis of the salivary glands may cause hyposalivation and xerostomia. Fibrosis of the perioral skin reduces the maximum opening of the mouth, thereby hampering dental treatment and the maintenance of oral hygiene. Periodontitis and bone resorption ofthe jaws are more frequently observed in systemic sclerosis patients.
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