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Related Concept Videos

Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

61
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal...
61
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
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Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

64
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

908
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
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Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

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Fulminant colitis.

Francisco Portela1, Paula Lago

  • 1Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.

Best Practice & Research. Clinical Gastroenterology
|October 29, 2013
PubMed
Summary
This summary is machine-generated.

Fulminant colitis, the most severe acute colitis, requires prompt medical care and timely surgery for non-responders. This approach is crucial for managing this severe gastrointestinal condition effectively.

Keywords:
Clostridium difficile colitisFulminant colitisSevere colitisUlcerative colitis

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery

Background:

  • Fulminant colitis is an ill-defined, severe form of acute colitis.
  • It often complicates ulcerative colitis and infectious colitis but can occur in other colitis types.

Purpose of the Study:

  • To define a systematic approach for managing patients with severe or fulminant colitis.

Main Methods:

  • Clinical criteria assessment for severe/fulminant colitis.
  • Implementation of a two-premise management strategy: intense medical therapy and early surgical intervention for non-responders.

Main Results:

  • A systematic approach is essential for patients meeting clinical criteria for severe or fulminant colitis.
  • Management hinges on aggressive medical treatment coupled with early surgical consideration for those not improving.

Conclusions:

  • Patients with fulminant colitis necessitate a structured management plan.
  • This plan prioritizes intensive medical treatment and early surgical intervention for non-responsive cases to improve outcomes.