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[Functional and motor digestive disorders].

Fermín Mearin1, Enrique Rey, Agustín Balboa

  • 1Instituto de Trastornos Funcionales y Motores Digestivos, Servicio de Aparato Digestivo, Centro Médico Teknon, Barcelona, España.

Gastroenterologia Y Hepatologia
|October 29, 2013
PubMed
Summary
This summary is machine-generated.

This review highlights key 2013 findings on functional gastrointestinal disorders (FGID), including their link to inflammatory bowel disease and fatigue. New insights into FGID causes, like early life factors and bile acids in irritable bowel syndrome (IBS), were presented.

Keywords:
AcalasiaDispepsia funcionalEnfermedad celíacaEstreñimiento funcionalFunctional gastrointestinal disorders ;Functional dyspepsia ;Irritable bowel syndrome ;Functional constipation ;Achalasia ;Celiac diseaseSíndrome del intestino irritableTrastornos funcionales digestivos

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Clinical Research

Context:

  • Digestive Diseases Week (DDW) 2013 showcased advancements in understanding functional and motility gastrointestinal disorders.
  • Functional gastrointestinal disorders (FGID) are increasingly recognized for their clinical significance and association with other conditions like inflammatory bowel disease and fatigue.
  • Emerging research points to environmental factors and early life events as potential contributors to FGID development.

Purpose:

  • To summarize significant findings on functional and motility gastrointestinal disorders presented at DDW 2013.
  • To highlight new data on the pathophysiology, clinical importance, and therapeutic strategies for FGID.
  • To inform clinicians about recent advancements relevant to irritable bowel syndrome (IBS), functional dyspepsia (FD), and constipation.

Summary:

  • New data indicate FGID can cause disturbances like inflammatory bowel disease and fatigue, with early life factors and environmental influences playing a role in their development.
  • Research explored the role of bile acids and food intake in irritable bowel syndrome (IBS) diarrhea, the link between IBS and celiac disease, and the limited benefit of indiscriminate gluten-free diets.
  • Studies on functional dyspepsia (FD) investigated psychological factors affecting gastric accommodation and their relation to visceral hypersensitivity and gastric emptying. Therapeutic options including mirtazapine, linaclotide, prucalopride, and plecanatide were discussed.
  • Diagnostic approaches for constipation, such as pelvic floor dyssynergy assessment, and novel treatments like botulinum toxin for esophageal motility disorders were presented.

Impact:

  • Provides a concise overview of critical updates in FGID research from DDW 2013.
  • Enhances understanding of FGID etiology, emphasizing the interplay of genetic, environmental, and psychological factors.
  • Informs clinical practice regarding diagnosis and management of various functional and motility gastrointestinal disorders, including IBS, FD, and constipation.
  • Highlights the importance of considering underlying conditions like celiac disease in IBS patients and evaluating new therapeutic agents.