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Percutaneous dilational tracheostomy in patients receiving antiplatelet therapy: is it safe?
Wissam Abouzgheib1, Nikhil Meena, Prashant Jagtap
1*Division of Pulmonary and Critical Care Medicine, Cooper University Hospital, Camden, NJ †Division of Pulmonary and Critical Care Medicine, University of Arkansas for Medical Sciences, Little Rock, AR.
Insights
Patients on antiplatelet therapy, specifically clopidogrel, can safely undergo percutaneous dilational tracheostomy (PDT). This study found no increased bleeding risk, supporting continuation of antiplatelet agents during PDT.
Area of Science:
- Cardiology
- Pulmonology
- Surgical Procedures
Background:
- Antiplatelet agents are crucial for vascular diseases but increase bleeding risk.
- Bleeding complications can compromise the safety of invasive procedures.
- Percutaneous dilational tracheostomy (PDT) is an invasive procedure requiring careful risk assessment.
Purpose of the Study:
- To evaluate the bleeding risk associated with percutaneous dilational tracheostomy (PDT) in patients taking antiplatelet therapy.
- To compare bleeding rates between patients on clopidogrel and a control group undergoing PDT.
Main Methods:
- Retrospective chart review of patients undergoing PDT across two institutions.
- Inclusion of a study group receiving clopidogrel and a control group.
- Analysis of bleeding complications (major and minor) post-PDT.
Main Results:
- No major bleeding events were reported in either the clopidogrel group or the control group.
- Minor bleeding occurred in 5% of the clopidogrel group versus 3.6% in the control group (P=0.85).
- The incidence of bleeding was not significantly different between the groups.
Conclusions:
- Percutaneous dilational tracheostomy (PDT) can be safely performed without discontinuing clopidogrel.
- Continuation of antiplatelet therapy is supported when there is a clear indication.
- This finding enhances procedural safety for patients requiring both PDT and antiplatelet medication.
Abstract:
Antiplatelet agents have become a mainstay therapy for vascular diseases; yet, it increases the risk of bleeding. The latter has a potential to impact the safety of invasive procedures. A retrospective chart review of patients undergoing percutaneous dilational tracheostomy (PDT) at each of the 2 institutions was performed to determine the bleeding risk for patients on antiplatelet therapy who underwent PDT. Out of the 246 patients who underwent PDT over the study period, 20 qualified for the study group. All were being treated with clopidogrel. A control group of 137 patients was created. No major bleeding occurred in either of the group. Minor bleeding occurred in 1 study patient (5%) and in 5 (3.6%) of the control patients (P=0.85). The data support the performance of PDT without stopping clopidogrel if there was a clear and ongoing indication for the antiplatelet agent.
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