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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

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Published on: March 9, 2018

Ulcerative tracheobronchitis due to Aspergillus.

Giulio S Dominelli¹, Tawimas Shaipanich

¹Department of Respiratory Medicine, University of British Columbia, Vancouver, BC, Canada.

Journal of Bronchology & Interventional Pulmonology

|October 29, 2013

Summary

This summary is machine-generated.

Aspergillus ulcerative tracheobronchitis, a severe invasive aspergillosis, can occur in non-immunocompromised patients. Bronchoscopists should consider this diagnosis when encountering mucosal erosions, particularly with risk factors like ICU admission.

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Area of Science:

Pulmonology
Infectious Diseases
Mycology

Background:

Invasive aspergillosis is a serious fungal infection.
Aspergillus ulcerative tracheobronchitis is a rare, life-threatening manifestation.
Typically affects immunocompromised individuals.

Observation:

Presents a case of invasive Aspergillus infection.
Involves widespread ulcerative tracheobronchitis.
Occurred in a 39-year-old man with asthma exacerbation.

Findings:

The patient required intensive care unit admission.
Unconventional risk factors included ICU stay and short-term glucocorticoid therapy.
Highlights the need for vigilance in diagnosing this condition.

Implications:

Bronchoscopists must recognize Aspergillus ulcerative tracheobronchitis.
Consider this diagnosis in cases of mucosal erosions.
Awareness of atypical risk factors is crucial for timely intervention.