Granulocytic sarcoma of the anterior mediastinum

Granulocytic sarcoma, or chloroma, rarely occurs in the anterior mediastinum. When it does, the clinical picture may resemble lymphoma. We report two patients in whom evaluation for mediastinal mass revealed the diagnosis of granulocytic sarcoma. In both patients, careful histopathologic evaluation with the aid of special stains confirmed the granulocytic origin of these tumors.