[Cytomegalovirus jejunitis diagnosed with single-balloon enteroscopy]

Area of Science:

• Gastroenterology
• Infectious Diseases
• Virology

Background:

• Cytomegalovirus (CMV) infections are typically observed in immunocompromised individuals.
• CMV jejunitis is a rare condition, often presenting with non-specific gastrointestinal symptoms.

Observation:

• A 74-year-old immunocompetent male presented with a month of abdominal pain and diarrhea.
• Abdominal CT revealed jejunal wall thickening; single-balloon enteroscopy identified multiple geographic ulcers in the proximal jejunum.
• Biopsies showed necrotic debris and ulceration, with CMV DNA detected by nested-PCR.

Findings:

• The patient was diagnosed with Cytomegalovirus (CMV) jejunitis.
• Intravenous ganciclovir treatment for 14 days led to symptom improvement.

Implications:

• This case highlights that CMV jejunitis can manifest in immunocompetent adults.
• Single-balloon enteroscopy is a valuable tool for diagnosing CMV-induced jejunal ulcers.
• Early diagnosis and treatment of CMV jejunitis can lead to favorable outcomes.