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Published on: March 27, 2018
Race and survival among diabetic patients after coronary artery bypass grafting
Wesley T O'Neal1, Jimmy T Efird2, Stephen W Davies3
1Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Insights
Long-term survival after coronary artery bypass grafting (CABG) was similar for black and white patients with diabetes. This study found no survival disadvantage for Black diabetic patients compared to White diabetic patients undergoing CABG.
Area of Science:
- Cardiovascular Surgery
- Diabetology
- Health Disparities
Background:
- Diabetes mellitus is a significant risk factor for reduced long-term survival following coronary artery bypass grafting (CABG).
- Existing research has not thoroughly examined potential racial differences in long-term survival outcomes among diabetic patients who have undergone CABG.
Purpose of the Study:
- To investigate and compare long-term survival rates in diabetic patients after CABG, specifically examining differences between Black and White individuals.
- To determine if race influences survival outcomes in diabetic patients undergoing this major cardiac procedure.
Main Methods:
- A retrospective cohort study analyzed data from 13,053 patients who underwent CABG between 1992 and 2011.
- Survival outcomes were compared between diabetic and non-diabetic patients, with analyses stratified by race.
- Cox regression models were utilized to calculate hazard ratios (HR) and 95% confidence intervals (CI) for long-term survival.
Main Results:
- The study included 35% of patients with diabetes at the time of surgery (1,655 Black patients, 2,884 White patients).
- Median follow-up was 8.2 years.
- Adjusted analyses revealed similar long-term survival for both Black and White diabetic patients (adjusted HR = 1.5 for both groups), indicating no significant difference in survival disadvantage based on race.
Conclusions:
- This study did not find evidence of a survival disadvantage for Black diabetic patients compared to White diabetic patients undergoing CABG.
- The findings suggest that race does not appear to be a significant factor in long-term survival outcomes for diabetic individuals after this procedure.
Background:
Diabetes is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined.
Methods:
A retrospective cohort study was conducted for CABG patients between 1992 and 2011. Long-term survival was compared in patients with and without diabetes and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model.
Results:
Out of the 13,053 patients undergoing CABG, 35% (black n = 1,655; white n = 2,884) had diabetes at the time of surgery. The median follow-up for study participants was 8.2 years. Long-term survival after CABG was similar between black and white diabetic patients (no diabetes, HR = 1.0; white diabetic patients, adjusted HR = 1.5, 95%CI = 1.4-1.6; black diabetic patients, adjusted HR = 1.5, 95%CI = 1.4-1.7).
Conclusion:
A survival disadvantage after CABG was not observed among black versus white diabetic patients in our study.
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