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Updated: May 6, 2026

Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
Published on: March 17, 2020
Interrupted development of dentition in children receiving bone marrow transplantation for acute lymphocytic
Chris Rowland1, Sue Kaste, Amber Owens
1Chief, Division of Dentistrym Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee; Adjunct Faculty, University of Tennessee School of Health Sciences, Memphis, Tennessee.
Abstract:
This case series depicts dental anomalies that may develop in children who have undergone bone marrow transplantation (BMT) for acute lymphoblastic leukemia (ALL). The most common finding in these patients was root stunting; other abnormalities included microdontia, hypodontia, taurodontia, caries, enamel pearls, and pulpal calcification. Recognition of these adverse effects of BMT on odontogenesis, as demonstrated on panoramic radiograph images, will allow healthcare providers to explain to parents and patients the possible dental outcomes associated with BMT and to optimize their dental health regimen.

