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Updated: May 6, 2026

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
Published on: October 16, 2010
No link between breast cancer and meningioma: results from a large monoinstitutional retrospective analysis
Carmen Criscitiello1, Davide Disalvatore, Michele Santangelo
1Authors' Affiliations: Breast Cancer Program, Division of Early Drug Development, Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan; and Department of Advanced Biomedical Sciences, Operative Unit of General Surgery and Transplants, University Naples Federico II, Napoli, Italy.
Background:
The etiology of meningioma is largely unknown, although breast cancer has been suggested to play a role.
Methods:
A monoinstitutional, retrospective analysis was performed at European Institute of Oncology on 12,330 patients with breast cancer. The cumulative incidence of meningioma was estimated using the Kaplan-Meier method and the log-rank test was used to assess differences between groups.
Results:
In total, 33 patients with meningioma were identified from a study population of 12,330, with a 10-year cumulative incidence of meningioma of 0.37%. We did not find a significantly increased risk of meningioma among patients with breast cancer or an association between the hormonal receptor status and the risk of meningioma (P = 0.65).
Conclusions:
Our results do not support a role of breast cancer or endocrine treatments in meningioma development.
Impact:
This analysis adds new information on a debated topic.
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