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Updated: May 6, 2026
Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
Published on: December 25, 2016
A paper indicator for triple-modality sensing of nitrite based on colorimetric assay, Raman spectroscopy, and
Zhibin Wang1, Jingfang Wang, Zhiwei Xiao
1Department of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Integrative NanoScience Institute, Florida State University, 2525 Pottsdamer Street, Tallahassee, Florida 32310, USA. guan@eng.fsu.edu.
Abstract:
Paper indicators based on colorimetric assays are widely used for nitrite detection, but their application to liquids with strong colours is restricted. We report a novel paper indicator that allows for sensing nitrite by colorimetric assay, Raman spectroscopy, and electron paramagnetic resonance spectroscopy with non-overlapping signal wavelength ranges through non-contact means. The paper indicator was prepared by impregnating poly(4-aminostyrene), 2-naphthol and single-walled carbon nanotubes in a regular filter paper. All three ingredients were essential to realize the triple-modality sensing. This method is simple and inexpensive, and promises to have wider applicability than the existing paper indicators.
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