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Updated: May 6, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Clinical characteristics and HPV type in recurrent respiratory papillomatosis in Colombia
Gustavo Cuello1, Gloria I Sánchez, Roberto Jaramillo
1Centro Médico Imbanaco, Cali, Colombia.
Objective:
Describe factors associated with aggressive forms of recurrent respiratory papillomatosis (RRP).
Materials And Methods:
One hundred eighty-nine RRP cases diagnosed between 1985 and 2009 were identified in pathological records. HPV was detected by the SPF-10 method with broad spectrum primers, (version 1).
Results:
113 patients had only one surgery (less aggressive) and 76, two or more interventions (more aggressive). The likelihood of aggressive lesions decreased with increasing age at diagnosis and HPV-11 was associated with no significant increase in the risk of aggressiveness.
Conclusions:
The age at diagnosis was the main determinant of RRP aggressiveness.
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