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The EuroNet paediatric hodgkin network - modern imaging data management for real time central review in multicentre
L Kurch1, C Mauz-Körholz, S Bertling
1Department of Nuclear Medicine, University Hospital of Leipzig, Germany.
Insights
The EuroNet Paediatric Hodgkin Data Network facilitates efficient, secure data sharing for children with Hodgkin lymphoma. This network improves multi-center trial quality control and therapy management through centralized image review.
Area of Science:
- Pediatric Oncology
- Clinical Trials
- Medical Imaging
Background:
- Children and adolescents with Hodgkin lymphoma are treated in Europe-wide EuroNet-PHL trials since 2007.
- Centralized review of cross-sectional images is crucial for patient stratification, quality control, and efficient therapy management.
- Time-critical reference evaluations necessitate fast, secure, and accessible data transfer.
Purpose of the Study:
- To describe the operational model of the EuroNet Paediatric Hodgkin Data Network.
- To highlight the advantages of centralized image review in multi-center pediatric Hodgkin lymphoma trials.
- To detail the data protection measures implemented within the network.
Main Methods:
- Establishment of the EuroNet Paediatric Hodgkin Data Network (2008-2011) funded by the European Union.
- Implementation of a real-time central review process for cross-sectional imaging.
- Development and application of a tailored data protection plan.
Main Results:
- The network ensures immediate and constant access to data for queries and regulatory compliance.
- Facilitates efficient therapy management through real-time patient stratification.
- Enhances quality control in multi-center clinical trials by centralizing image review.
Conclusions:
- The EuroNet Paediatric Hodgkin Data Network provides a robust framework for multi-center pediatric Hodgkin lymphoma trials.
- Centralized image review is advantageous for quality control and efficient management.
- Secure and accessible data management is essential for international clinical research.
Abstract:
Since 2007, children and adolescents with Hodgkin lymphomas are treated in the Europe-wide EuroNet-PHL trials. A real time central review process for stratification of the patients enhances quality control and efficient therapy management. This process includes reading of all cross-sectional-images. Since reference evaluation is time critical, a fast, easy to handle and safe data transfer is important. In addition, immediate and constant access to all the data has to be guaranteed in case of queries and for regulatory reasons. To meet the mentioned requirements the EuroNet Paediatric Hodgkin Data Network (funded by the European Union - Project Number: 2007108) was established between 2008 and 2011. A respective tailored data protection plan was formulated. The aim of this article is to describe the networks' mode of operation and the advantages for multi-centre trials that include centralized image review.
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