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Assessing medication adherence: options to consider.
Audrey Lehmann1, Parisa Aslani, Rana Ahmed
1Univ. Grenoble-Alpes, 38041, Grenoble, France.
International Journal of Clinical Pharmacy
|October 30, 2013
Summary
Understanding medication adherence is crucial for chronic disease management. This review highlights common indirect adherence measures, finding no single gold standard exists, and recommends method standardization for reliable data.
Area of Science:
- Pharmacology
- Health Services Research
- Patient Outcomes
Background:
- Medication adherence is vital for managing chronic diseases, yet approximately 50% of patients do not adhere to their prescribed chronic therapy.
- Accurate assessment of adherence rates and non-adherence factors is essential for improving patient outcomes.
- Numerous methods exist to evaluate patient medication adherence.
Purpose of the Study:
- To review commonly utilized indirect methods for measuring medication adherence.
- To present these methods as applied in routine healthcare and research settings.
Main Methods:
- A literature review was conducted using Medline (2003-2013) focusing on medication adherence measures in chronic condition patients.
- A manual search of cited references identified additional relevant studies.
Main Results:
- The review identified patient self-report (50 publications), electronic measures (33), pharmacy refills and claims data (26), and pill counts (25) as common adherence measures.
- Patient self-report, electronic measures, and pharmacy data were most frequently used in research and practice.
- Strengths and limitations of these indirect adherence measurement methods are discussed.
Conclusions:
- No single "gold" standard exists for measuring medication adherence.
- Combining multiple methods (triangulation) enhances the validity and reliability of adherence data.
- Standardized definitions and clear reporting of adherence methods are recommended for future research and practice to improve data comparability.
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