Related Experiment Video
Updated: May 6, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
[Treatment of depression in patients with epilepsy]
Magdalena Bosak1, Dominika Dudek, Marcin Siwek
1Katedra i Klinika Neurologii, Collegium Medicum, Uniwersytetu Jagiellońskiego, Kraków. magdalenabosak@wp.pl
Abstract:
Depression is one of the most frequent comorbid psychiatric disorders in epilepsy. Comorbid depression in epilepsy affects negatively health-related quality of life, increases the risk for suicide and costs of medical care when compared to patients without depression. Unfortunately, affective disorders are underrecognized, and appropriate treatment is infrequent. The purpose of this article is to review strategies used in the pharmacologic treatment of depression in patients with epilepsy, choice of antidepressants, effects of antidepressants on seizure threshold, pharmacokinetic interactions between antidepressant drugs and antiepileptic drugs and psychotropic properties of antiepileptic drugs.
More Related Videos
08:20MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
09:07Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Related Concept Videos
Electroconvulsive Therapy
Antidepressant Drugs: MAOIs and Other Agents
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...
Antiepileptic Drugs: Glutamate Antagonists
Antiepileptic Drugs: GABAergic Pathway Potentiators
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...