Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

635
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
635
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

420
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
420
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence01:22

Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

260
Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
260
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

485
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
485
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

2.4K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
2.4K
Substitution Rule Applied to Indefinite Integrals01:27

Substitution Rule Applied to Indefinite Integrals

226
When a force is applied to a linear spring, the restoring force increases proportionally with the amount of displacement. This behavior is described by Hooke’s law, which allows the work done on the spring to be determined directly from the force–displacement relationship. In this case, the force varies in a simple and predictable manner, making the calculation relatively simple.On the other hand, a nonlinear spring does not obey Hooke’s law. Its restoring force depends on...
226

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethics and Controversies in Animal Subjects Research and Impact on Clinical Decision-Making.

Anesthesiology clinics·2024
Same author

60 Years of the 3Rs symposium: Lessons learned and the road ahead.

ALTEX·2024
Same author

<i>Alternatives to Laboratory Animals</i>: Trends in <i>Replacement</i> and the Three Rs.

Alternatives to laboratory animals : ATLA·2022
Same author

Clinical impact of high-profile animal-based research reported in the UK national press.

BMJ open science·2022
Same author

It's Time to Include Harm to Humans in Harm-Benefit Analysis - But How to Do It, That is the Question.

Alternatives to laboratory animals : ATLA·2021
Same author

It's Time to Reconsider <i>The Principles of Humane Experimental Technique</i>.

Alternatives to laboratory animals : ATLA·2020
Same journal

Spotlight on Three Rs Progress.

Alternatives to laboratory animals : ATLA·2026
Same journal

Resources Round-up.

Alternatives to laboratory animals : ATLA·2026
Same journal

Editorial.

Alternatives to laboratory animals : ATLA·2026
Same journal

<i>Galleria mellonella</i> as an invertebrate screening model for biocompatibility and <i>in vivo</i> functionality testing of imaging contrast agents.

Alternatives to laboratory animals : ATLA·2026
Same journal

Data-driven science, ethics and risk: Building knowledge of key ethics-risk intersections relevant to public sector decision-making.

Alternatives to laboratory animals : ATLA·2026
Same journal

Conference Diary.

Alternatives to laboratory animals : ATLA·2026
See all related articles

Related Experiment Video

Updated: May 6, 2026

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

22.1K

6. Replacement

Michael Balls1

  • 1FRAME, Nottingham, UK.

Alternatives to Laboratory Animals : ATLA
|October 31, 2013
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
09:01

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

12.0K
Dissection of 6.5 dpc Mouse Embryos
09:57

Dissection of 6.5 dpc Mouse Embryos

Published on: February 25, 2007

38.8K

Related Experiment Videos

Last Updated: May 6, 2026

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

22.1K
Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
09:01

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

12.0K
Dissection of 6.5 dpc Mouse Embryos
09:57

Dissection of 6.5 dpc Mouse Embryos

Published on: February 25, 2007

38.8K