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Updated: May 6, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
My urge, my tic - a missing link between urges and tic inhibition
1a Movement Disorders Research Group, Department of Neurology , University Medical Center Hamburg-Eppendorf (UKE) , Hamburg , Germany.
None:
Abstract Despite the fact that premonitory urges precede most tics in patients with Gilles de la Tourette syndrome (GTS), the voluntariness of tic elicitation and its suppressibility as a response to these urges still remains unclear. Moreover, there are no systematic studies examining the association between urge intensity and the ability to suppress tics. As shown by behavioral, neurophysiological, and imaging data, sensorimotor networks in GTS exhibit altered patterns of organization modulated through interactions with frontomesial networks of volitional inhibition.
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