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Updated: May 6, 2026

CMAP Scan MUNE MScan - A Novel Motor Unit Number Estimation MUNE Method
Published on: June 7, 2018
Reliability of a modified motor unit number index (MUNIX) technique
Ryan D Kaya1, Richard L Hoffman2, Brian C Clark2
1Ohio Musculoskeletal and Neurological Institute (OMNI) at Ohio University, Athens, OH, United States; School of Applied Health Sciences and Wellness at Ohio University, Athens, OH, United States.
Introduction:
The purpose of this study was to examine the relative and absolute between-day reliability of the motor unit number index (MUNIX).
Methods:
Young, healthy adults (n=19) attended two testing sessions separated by 4-weeks where their maximal pinch-grip strength, MUNIX, and motor unit size index (MUSIX) were assessed in the abductor pollicis brevis muscle. Reliability was assessed by intraclass correlation coefficients (ICC), coefficient of variation (CV) and limits of agreement (LOA).
Results:
No mean differences were observed for MUNIX or MUSIX. The CV for the MUNIX and MUSIX measures were between 13.5% and 17.5%. The ICC for both measures were moderate to moderately-high (0.73-0.76), The LOA for both indicated a homoscedastic relationship.
Discussion:
Our findings indicate moderate to moderately-high reliability for both MUNIX and MUSIX. Future work is needed to ensure both measures are reliable in other muscles and cohorts, and further investigations are required to examine the validity of MUNIX.
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