Related Experiment Video
Updated: May 6, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Correlation of cardiovascular risk factors and cognitive function]
Xiao-nan Wang1, Xiao-juan Bai, Jing Liu
1Departments of Gerontology & Geriatrics, First Affiliated Hospital, China Medical University, Shenyang 110001, China.
Cardiovascular risk factors negatively impact cognitive function in healthy adults. Higher Framingham risk scores correlate with decreased performance on cognitive tests, indicating a need for risk management.
Area of Science:
- Cardiology
- Neurology
- Public Health
Context:
- Cardiovascular disease risk factors are prevalent in the general population.
- Cognitive decline is a growing public health concern.
- Understanding the link between cardiovascular health and brain function is crucial.
Purpose:
- To investigate the association between cardiovascular risk factors and cognitive function.
- To evaluate cognitive performance across different levels of 10-year coronary heart disease (CHD) risk.
- To determine the correlation between the Framingham Risk Score (FRS) and cognitive test results.
Summary:
- A cross-sectional study in Shenyang assessed 505 healthy adults using the Framingham Risk Score and cognitive tests (Clock Drawing Test, MMSE).
- Participants were categorized into low, moderate, and high 10-year CHD risk groups.
- Results showed significantly lower cognitive function scores in moderate and high-risk groups compared to the low-risk group, with an inverse correlation between FRS and cognitive performance.
Impact:
- Highlights the detrimental effect of cardiovascular risk factors on cognitive function in a healthy population.
- Emphasizes the importance of managing cardiovascular health for maintaining cognitive abilities.
- Provides evidence supporting the integration of cognitive health assessments within cardiovascular risk management strategies.
Related Concept Videos
Coronary Artery Disease I: Introduction
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Coronary Artery Disease IV: Preventive Measures
Factors affecting Blood pressure
Physiological Factors:
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...

