Relationship between vegetable and carotene intake and risk of prostate cancer: the JACC study
Background:
We examined the associations of intakes of vegetables and carotenes with risk of prostate cancer in Japanese.
Methods:
A total of 15,471 Japanese men participating in the Japan Collaborative Cohort study completed a questionnaire including food intake. Of them, 143 incident prostate cancers were documented. We examined the associations stated above by using Cox proportional hazard model.
Results:
Vegetable intake was not associated with the risk of prostate cancer, but so was dietary alpha-carotene intake. The multivariable hazard ratio (95%CI) in the secondary highest and highest quintiles of alpha-carotene intake was 0.50 (0.26-0.98) (P=0.043) and 0.46 (0.22-0.97) (P=0.041) (P for trend=0.224), respectively. Beta-carotene intake was not associated with the risk of prostate cancer.
Conclusion:
Alpha-carotene intake was associated with lower risk of prostate cancer among Japanese.
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