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Updated: May 6, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
[ESC guidelines on the management of valvular heart disease. What has changed and what is new?]
1Klinik für Innere Medizin/ Kardiologie, Herzzentrum Leipzig - Universitätsklinik, Strümpellstr. 39, 04289, Leipzig, Deutschland.
Insights
The 2012 European guidelines for valvular heart disease management emphasize a "heart team" approach. Key updates include aortic regurgitation thresholds for Marfan syndrome and indications for transcatheter aortic valve implantation (TAVI).
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Clinical Guidelines
Context:
- The 2012 European Society of Cardiology (ESC) and European Association for Cardio-Thoracic Surgery (EACTS) guidelines provide a framework for managing valvular heart disease.
- Decision-making requires a multidisciplinary "heart team" with specialized expertise.
Purpose:
- To summarize and highlight key recommendations from the 2012 ESC/EACTS guidelines on valvular heart disease management.
- To detail specific indications and considerations for surgical and transcatheter interventions in aortic and mitral valve pathologies.
- To address management strategies for aortic regurgitation, aortic stenosis, mitral regurgitation, and tricuspid disease.
Summary:
- For aortic regurgitation in Marfan syndrome, surgery is indicated at a ≥50 mm ascending aorta diameter, with lower thresholds for high-risk patients.
- Transcatheter aortic valve implantation (TAVI) is recommended for severe symptomatic aortic stenosis in patients unsuitable for surgery, requiring a "heart team" assessment and performed in specialized centers.
- Mitral regurgitation management favors durable valve repair, with percutaneous edge-to-edge repair as an option for high-risk patients. Tricuspid valve surgery should be considered during left-sided procedures if indicated. Low-dose aspirin is favored post-aortic bioprosthesis implantation.
Impact:
- These guidelines promote standardized, expert-driven care for valvular heart disease patients.
- The emphasis on the "heart team" ensures comprehensive risk assessment and tailored treatment strategies.
- Updates on TAVI and mitral valve repair expand treatment options, particularly for high-risk or complex cases.
Abstract:
In 2012 the new and collaborative "Guidelines on the management of valvular heart disease (version 2012)" were published by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). These guidelines emphasize that decision-making in patients with valvular heart disease should ideally be carried out by a"heart team" with particular expertise in valvular heart disease. In aortic regurgitation pathologies of the aortic root are frequent and in patients with Marfan syndrome, surgery is indicated when the maximal ascending aortic diameter is ≥50 mm, while the threshold for intervention should be lower in patients with risk factors for progression. Regarding aortic stenosis, transcatheter aortic valve implantation (TAVI) should be performed only in hospitals with on-site cardiac surgery and with a"heart team" available to assess patient risks. The TAVI procedure is indicated in patients with severe symptomatic aortic stenosis who are judged by the"heart team" to be unsuitable for surgery but have sufficient life expectancy. It should be considered for high-risk patients with severe symptomatic aortic stenosis based on the individual risk profile assessed by the"heart team". Furthermore, low flow - low gradient aortic stenosis with normal ejection fraction and the difficult topic of asymptomatic severe aortic stenosis and the indications for aortic valve replacement are discussed. With respect to mitral regurgitation, valve repair should be the preferred technique when it is expected to be durable. The topics of asymptomatic mitral regurgitation as well as percutaneous mitral valve repair using the edge to edge technique as an alternative for high risk patients are discussed. Tricuspid disease should not be forgotten and during left-sided valve surgery, tricuspid valve surgery should be considered in the presence of mild to moderate secondary regurgitation if there is significant annular dilatation. Last but not least, in patients with aortic bioprostheses the use of low-dose aspirin is now favored for a 3-month postoperative period.
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