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Updated: May 6, 2026

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
Published on: October 2, 2019
Sleep in childhood and adolescence: age-specific sleep characteristics, common sleep disturbances and associated
Nicola L Barclay1, Alice M Gregory
1Department of Psychology, Faculty of Health and Life Sciences, Northumbria Centre for Sleep Research, Northumbria University, Newcastle Upon Tyne, London, NE1 8ST, UK, nicola.barclay@northumbria.ac.uk.
Insights
Childhood sleep patterns evolve due to brain development and circadian system changes. Sleep disturbances are common in children and can be linked to behavioral issues or other developmental disorders.
Area of Science:
- Neuroscience
- Developmental Psychology
- Sleep Medicine
Background:
- Sleep undergoes significant transformations across the lifespan, particularly in early childhood and adolescence.
- These changes are influenced by brain maturation, circadian system organization, and environmental factors.
- Sleep disturbances are prevalent in children, often linked to behavioral or physiological issues, and can develop into diagnosable disorders.
Purpose of the Study:
- To detail the neurobiology of typical sleep-wake cycles from birth to adulthood.
- To describe developmental changes in sleep physiology and architecture.
- To explore common childhood sleep disorders and their associations with conditions like ASDs, ADHD, schizophrenia, and emotional/behavioral difficulties.
Main Methods:
- Review of neurobiological mechanisms governing sleep-wake processes.
- Analysis of age-related changes in sleep physiology and architecture.
- Examination of associations between childhood sleep disorders and other neurodevelopmental/behavioral conditions.
Main Results:
- Typical sleep-wake processes are governed by complex neurobiological mechanisms.
- Sleep architecture and physiology exhibit distinct developmental trajectories.
- Childhood sleep disturbances frequently co-occur with other developmental and behavioral challenges.
Conclusions:
- Understanding the neurobiology of sleep is crucial for identifying and managing childhood sleep disturbances.
- Sleep disorders in children often share underlying mechanisms with other neurodevelopmental conditions.
- Further research into these associations can inform integrated treatment approaches.
Abstract:
Sleep changes throughout the lifespan, with particularly salient alterations occurring during the first few years of life, as well as during the transition from childhood to adolescence. Such changes are partly the result of brain maturation; complex changes in the organisation of the circadian system; as well as changes in daily routine, environmental demands and responsibilities. Despite the automaticity of sleep, given that it is governed by a host of complex mechanisms, there are times when sleep becomes disturbed. Sleep disturbances in childhood are common and may stem from behavioural difficulties or abnormalities in physiological processes-and, in some cases manifest into diagnosable sleep disorders. As well as occurring exclusively, childhood sleep disturbances often co-occur with other difficulties. The purpose of this chapter is to outline the neurobiology of typical sleep/wake processes, and describe changes in sleep physiology and architecture from birth to adulthood. Furthermore, common childhood sleep disorders are described as are their associations with other traits, including all of the syndromes presented in this handbook: ASDs, ADHD, schizophrenia and emotional/behavioural difficulties. Throughout, we attempt to explain possible mechanisms underlying these disorders and their associations.
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