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Pelvic exenteration.

W F Lindsey, D K Wood, H A Briele

    Journal of Surgical Oncology
    |December 1, 1985
    PubMed
    Summary
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    Pelvic exenteration is a viable surgical option for advanced pelvic cancers, offering curative potential and effective palliation for symptomatic patients. This procedure demonstrated a low 30-day mortality and a 33% 5-year survival rate in selected cases.

    Area of Science:

    • Oncology
    • Surgical Oncology
    • Gastrointestinal Surgery

    Background:

    • Advanced pelvic malignancies pose significant treatment challenges.
    • Pelvic exenteration is a radical surgical approach for locally advanced pelvic tumors.
    • Historically, its role in curative and palliative settings requires ongoing evaluation.

    Purpose of the Study:

    • To evaluate the feasibility and outcomes of pelvic exenteration for advanced pelvic malignancies.
    • To assess survival rates and postoperative mortality associated with the procedure.
    • To determine the efficacy of pelvic exenteration in both curative and palliative contexts.

    Main Methods:

    • Retrospective analysis of 68 patients undergoing pelvic exenteration between 1969 and 1984.
    • Categorization of malignancies including colorectal, cervical, bladder, vulvar, and miscellaneous pelvic sites.

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  • Distinction between curative intent and palliative procedures based on tumor burden and symptoms.

    • Main Results:

    • The study included 68 patients with diverse pelvic cancers (colorectal, cervical, bladder, vulvar, etc.).
    • Forty-five procedures were for curative intent, while 23 were for palliation of symptomatic advanced disease.
    • The 30-day postoperative mortality was 4.4% (3/68), and the 5-year survival for curative cases was 33% (median 27 months).

    Conclusions:

    • Pelvic exenteration is a feasible surgical option for various advanced pelvic cancers.
    • The procedure offers both curative potential and effective palliation for severely symptomatic patients.
    • Outcomes suggest a manageable mortality and survival benefit in carefully selected patient cohorts.